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Magic™ Membrane Protein Human JAG1 (Jagged canonical Notch ligand 1) Expressed in Mammalian cell expression system with FC and Myc tag at the C-terminus for Antibody Discovery, Partial (185-334aa) (CAT#: MPX4108K)

Datasheet
This product is a 46.8 kDa Human JAG1 membrane protein expressed in Mammalian cell expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • JAG1
  • Protein Length
  • Partial (185-334aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 46.8 kDa
  • TMD
  • 1
  • Sequence
  • VTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE

Product Description

  • Expression Systems
  • Mammalian cell expression system
  • Tag
  • FC and Myc tag at the C-terminus
  • Protein Format
  • Soluble
  • Purity
  • >85% as determined by SDS-PAGE
  • Buffer
  • Tris-based buffer, 50% glycerol

Target

  • Target Protein
  • JAG1
  • Full Name
  • Jagged canonical Notch ligand 1
  • Introduction
  • The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
  • Alternative Names
  • JAG1; AGS; AHD; AWS; HJ1; AGS1; DCHE; CD339; JAGL1; protein jagged-1; Jagged canonical Notch ligand 1

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