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Magic™ Membrane Protein Human JPH3 (Junctophilin 3) Full Length (CAT#: MPC1059K) Made to Order

Datasheet
This product is a 81.4 kDa Human JPH3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • JPH3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 81.4 kDa
  • TMD
  • 1
  • Sequence
  • MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVL
    GVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVREC
    AGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPY
    GMAAVIRSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGGFVLVA
    HSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGM
    STVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGF
    GVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKN
    LIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALT
    AAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTG
    TPLQQESPELYRKGTTPSDLTPDDSPLQSFPTSPAATPPPAPAARNKVAH
    FSRQVSVDEERGGDIQMLLEGRAGDCARSSWGEEQAGGSRGVRSGALRGG
    LLVDDFRTRGSGRKQPGNPKPRERRTESPPVFTWTSHHRASNHSPGGSRL
    LELQEEKLSNYRMEMKPLLRMETHPQKRRYSKGGACRGLGDDHRPEDRGF
    GVQRLRSKAQNKENFRPASSAEPAVQKLASLRLGGAEPRLLRWDLTFSPP
    QKSLPVALESDEENGDELKSSTGSAPILVVMVILLNIGVAILFINFFI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • JPH3
  • Full Name
  • Junctophilin 3
  • Introduction
  • Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansion from normally 6-28 repeats to 40-59 repeats in the 3' UTR of this gene have been associated with Huntington disease-like 2 (HDL2). This gene is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene.
  • Alternative Names
  • JPH3; JP3; HDL2; JP-3; TNRC22; CAGL237; junctophilin-3; junctophilin type 3; trinucleotide repeat containing 22; Trinucleotide repeat-containing gene 22 protein; Junctophilin 3

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