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Magic™ Membrane Protein Human KCNA10 (Potassium voltage-gated channel subfamily A member 10) Full Length (CAT#: MPC0584K) Made to Order

Datasheet
This product is a 57.7 kDa Human KCNA10 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNA10
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 57.7 kDa
  • TMD
  • 6
  • Sequence
  • MDVCGWKEMEVALVNFDNSDEIQEEPGYATDFDSTSPKGRPGGSSFSNGK
    ILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRFETQ
    LRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGK
    IRRPANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHR
    QFWLLFEYPESSSAARAVAVVSVLVVVISITIFCLETLPEFREDRELKVV
    RDPNLNMSKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFF
    RNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFR
    IFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDE
    PESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIA
    LPVPVIVSNFNYFYHRETENEEKQNIPGEIERILNSVGSRMGSTDSLNKT
    NGGCSTEKSRK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNA10
  • Full Name
  • Potassium voltage-gated channel subfamily A member 10
  • Introduction
  • Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.
  • Alternative Names
  • Kcn1; Kv1.8; potassium voltage-gated channel subfamily A member 10; cyclic GMP gated potassium channel; potassium channel, voltage gated shaker related subfamily A, member 10; potassium voltage-gated channel, shaker-related subfamily, member 10; voltage-gated potassium channel subunit Kv1.8; KCNA10; Potassium voltage-gated channel subfamily A member 10

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