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Magic™ Membrane Protein Human KCNA7 (Potassium voltage-gated channel subfamily A member 7) Full Length (CAT#: MPC0583K) Made to Order

Datasheet
This product is a 50.5 kDa Human KCNA7 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNA7
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 50.5 kDa
  • TMD
  • 6
  • Sequence
  • MEPRCPPPCGCCERLVLNVAGLRFETRARTLGRFPDTLLGDPARRGRFYD
    DARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYGLGA
    AALARLREDEGCPVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSV
    LVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNP
    PRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAI
    LPYFVALGTELARQRGVGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQI
    LGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFW
    WAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYF
    YHRETEGEEAGMFSHVDMQPCGPLEGKANGGLVDGEVPELPPPLWAPPGK
    HLVTEV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNA7
  • Full Name
  • Potassium voltage-gated channel subfamily A member 7
  • Introduction
  • Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. It is a candidate gene for inherited cardiac disorders.
  • Alternative Names
  • HAK6; KV1.7; potassium voltage-gated channel subfamily A member 7; potassium channel, voltage gated shaker related subfamily A, member 7; potassium voltage-gated channel, shaker-related subfamily, member 7; voltage-dependent potassium channel Kv1.7; voltage-gated potassium channel KCNA7; voltage-gated potassium channel subunit Kv1.7; KCNA7; Potassium voltage-gated channel subfamily A member 7

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