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Magic™ Membrane Protein Human KCND3 (Potassium voltage-gated channel subfamily D member 3) Full Length (CAT#: MPC0593K) Made to Order

Datasheet
This product is a 73.4 kDa Human KCND3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCND3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 73.4 kDa
  • TMD
  • 6
  • Sequence
  • MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRR
    FQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRT
    GKLHYPRYECISAYDDELAFYGILPEIIGDCCYEEYKDRKRENAERLMDD
    NDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITN
    VVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLLRLFAAPS
    RYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
    SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASK
    FTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVP
    VIVSNFSRIYHQNQRADKRRAQKKARLARIRVAKTGSSNAYLHSKRNGLL
    NEALELTGTPEEEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDPLLSV
    RTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHPGLTTTCCSRR
    SKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
    LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVV
    KVSAL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCND3
  • Full Name
  • Potassium voltage-gated channel subfamily D member 3
  • Introduction
  • Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
  • Alternative Names
  • KV4.3; SCA19; SCA22; BRGDA9; KCND3L; KCND3S; KSHIVB; potassium voltage-gated channel subfamily D member 3; potassium channel, voltage gated Shal related subfamily D, member 3; potassium ionic channel Kv4.3; potassium voltage-gated channel long; potassium voltage-gated channel, Shal-related subfamily, member 3; sha1-related potassium channel Kv4.3; voltage-gated K+ channel; voltage-gated potassium channel subunit Kv4.3; KCND3; Potassium voltage-gated channel subfamily D member 3

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