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Magic™ Membrane Protein Human KCNH3 (Potassium voltage-gated channel subfamily H member 3) Full Length (CAT#: MPC0596K) Made to Order

This product is a 117.1 kDa Human KCNH3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNH3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 117.1 kDa
  • TMD
  • 6
  • Sequence
  • MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFC
    DLTGFSRAEVMQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILY
    RKSGLPFWCLLDVIPIKNEKGEVALFLVSHKDISETKNRGGPDRWKETGG
    GRRRYGRARSKGFNANRRRSRAVLYHLSGHLQKQPKGKHKLNKGVFGEKP
    NLPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAVTVPYSVCVST
    AREPSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICL
    HYVTTWFLLDVIAALPFDLLHAFKVNVYFGAHLLKTVRLLRLLRLLPRLD
    RYSQYSAVVLTLLMAVFALLAHWVACVWFYIGQREIESSESELPEIGWLQ
    ELARRLETPYYLVGRRPAGGNSSGQSDNCSSSSEANGTGLELLGGPSLRS
    AYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNV
    TAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNN
    GIDTTELLQSLPDELRADIAMHLHKEVLQLPLFEAASRGCLRALSLALRP
    AFCTPGEYLIHQGDALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELP
    RREQVVKANADVKGLTYCVLQCLQLAGLHDSLALYPEFAPRFSRGLRGEL
    SYNLGAGGGSAEVDTSSLSGDNTLMSTLEEKETDGEQGPTVSPAPADEPS
    SPLLSPGCTSSSSAAKLLSPRRTAPRPRLGGRGRPGRAGALKAEAGPSAP
    PRALEGLRLPPMPWNVPPDLSPRVVDGIEDGCGSDQPKFSFRVGQSGPEC
    SSSPSPGPESGLLTVPHGPSEARNTDTLDKLRQAVTELSEQVLQMREGLQ
    SLRQAVQLVLAPHREGPCPRASGEGPCPASTSGLLQPLCVDTGASSYCLQ
    PPAGSVLSGTWPHPRPGPPPLMAPWPWGPPASQSSPWPRATAFWTSTSDS
    EPPASGDLCSEPSTPASPPPSEEGARTGPAEPVSQAEATSTGEPPPGSGG
    LALPWDPHSLEMVLIGCHGSGTVQWTQEEGTGV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNH3
  • Full Name
  • Potassium voltage-gated channel subfamily H member 3
  • Introduction
  • The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • BEC1; ELK2; Kv12.2; potassium voltage-gated channel subfamily H member 3; ELK channel 2; brain-specific eag-like channel 1; ether-a-go-go K(+) channel family member; ether-a-go-go-like potassium channel 2; potassium channel, voltage gated eag related subfamily H, member 3; potassium voltage-gated channel, subfamily H (eag-related), member 3; voltage-gated potassium channel subunit Kv12.2; KCNH3; Potassium voltage-gated channel subfamily H member 3

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