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Magic™ Membrane Protein Human KCNK4 (Potassium two pore domain channel subfamily K member 4) Full Length (CAT#: MPC0626K) Made to Order

This product is a 42.7 kDa Human KCNK4 membrane protein expressed in Komagataella pastoris. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNK4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 42.7 kDa
  • TMD
  • 4
  • Sequence
  • MRSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAH
    PCVSDQELGLLIKEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTI
    ITTIGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRHGI
    GHIEAIFLKWHVPPELVRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKL
    EAIYFVIVTLTTVGFGDYVAGADPRQDSPAYQPLVWFWILLGLAYFASVL
    TTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTARVTQRAGPAAPPPEKE
    QPLLPPPPCPAQPLGRPRSPSPPEKAQPPSPPTASALDYPSENLAFIDES
    SDTQSERGCPLPRAPRGRRRPNPPRKPVRPRGPGRPRDKGVPV

Product Description

  • Expression Systems
  • Komagataella pastoris
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNK4
  • Full Name
  • Potassium two pore domain channel subfamily K member 4
  • Introduction
  • This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802.
  • Alternative Names
  • FHEIG; TRAAK; K2p4.1; TRAAK1; potassium channel subfamily K member 4; K2P4.1 potassium channel; TWIK-related arachidonic acid-stimulated potassium channel protein; potassium channel, subfamily K, member 4; potassium channel, two pore domain subfamily K, member 4; two pore K(+) channel KT4.1; two pore K+ channel KT4.1; two pore potassium channel KT4.1; KCNK4; Potassium two pore domain channel subfamily K member 4

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