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Magic™ Membrane Protein Human KCNT1 (Potassium sodium-activated channel subfamily T member 1) Full Length (CAT#: MPC0643K) Made to Order

Datasheet
This product is a 138.3 kDa Human KCNT1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KCNT1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 138.3 kDa
  • TMD
  • 6
  • Sequence
  • MARAKLPRSPSEGKAGPGGAPAGAAAPEEPHGLSPLLPARGGGSVGSDVG
    QRLPVEDFSLDSSLSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFN
    FSLKLLTCLLYIVRVLLDDPALGIGCWGCPKQNYSFNDSSSEINWAPILW
    VERKMTLWAIQVIVAIISFLETMLLIYLSYKGNIWEQIFRVSFVLEMINT
    LPFIITIFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFN
    QVLILFCTLLCLVFTGTCGIQHLERAGENLSLLTSFYFCIVTFSTVGYGD
    VTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQ
    TEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRV
    LQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADH
    QTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLAL
    NCICPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDS
    KFFREYEGKSFTYAAFHAHKKYGVCLIGLKREDNKSILLNPGPRHILAAS
    DTCFYINITKEENSAFIFKQEEKRKKRAFSGQGLHEGPARLPVHSIIASM
    GTVAMDLQGTEHRPTQSGGGGGGSKLALPTENGSGSRRPSIAPVLELADS
    SALLPCDLLSDQSEDEVTPSDDEGLSVVEYVKGYPPNSPYIGSSPTLCHL
    LPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIV
    PLRAYYRSRKELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSL
    LQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITT
    ELTHPSNMRFMQFRAKDSYSLALSKLEKRERENGSNLAFMFRLPFAAGRV
    FSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEGDLWI
    RTYGRLFQKLCSSSAEIPIGIYRTESHVFSTSESQISVNVEDCEDTREVK
    GPWGSRAGTGGSSQGRHTGGGDPAEHPLLRRKSLQWARRLSRKAPKQAGR
    AAAAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTAS
    DVMNRVNLGYLQDEMNDHQNTLSYVLINPPPDTRLEPSDIVYLIRSDPLA
    HVASSSQSRKSSCSHKLSSCNPETRDETQL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • KCNT1
  • Full Name
  • Potassium sodium-activated channel subfamily T member 1
  • Introduction
  • Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • DEE14; ENFL5; SLACK; EIEE14; KCa4.1; Slo2.2; bA100C15.2; potassium channel subfamily T member 1; Sequence like a calcium-activated K+ channel; potassium channel, sodium activated subfamily T, member 1; potassium channel, subfamily T, member 1; KCNT1; Potassium sodium-activated channel subfamily T member 1

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