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Magic™ Membrane Protein Human KIRREL3 (Kirre like nephrin family adhesion molecule 3) Full Length (CAT#: MPC3794K) Made to Order

Datasheet
This product is a made-to-order Human KIRREL3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KIRREL3
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MKPFQLDLLFVCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQVYSF
    SQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYL
    VVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDP
    VILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLL
    RDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPP
    LVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYR
    TTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGS
    DAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRA
    VVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDR
    IAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIVRADFQTIYNCT
    AWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLV
    LMATIVAFCCARSQRNLKGVVSAKNDIRVEIVHKEPASGREGEEHSTIKQ
    LMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTP
    TISLSSCQPDLRPAGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMG
    SSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKAS
    ASSSHHSQSSSQNSDPSRPLQRRMQTHV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • KIRREL3
  • Full Name
  • Kirre like nephrin family adhesion molecule 3
  • Introduction
  • The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • KIRREL3; MRD4; KIRRE; NEPH2; PRO4502; kin of IRRE-like protein 3; kin of IRRE like 3; kin of irregular chiasm-like protein 3; nephrin-like 2; nephrin-like protein 2; Kirre like nephrin family adhesion molecule 3

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