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Magic™ Membrane Protein Human KLRC3 (Killer cell lectin like receptor C3) Full Length (CAT#: MPC2340K) Made to Order

This product is a made-to-order Human KLRC3 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • KLRC3
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MSKQRGTFSEVSLAQDPKWQQRKPKGNKSSISGTEQEIFQVELNLQNASL
    NHQGIDKIYDCQGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPFLEQN
    NSSPNARTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLQACASKNS
    SSLLCIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHEIKDS
    DHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLNS

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • KLRC3
  • Full Name
  • Killer cell lectin like receptor C3
  • Introduction
  • Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • KLRC3; NKG2E; NKG2-E; NKG2-E type II integral membrane protein; NK cell receptor E; NKG2-E-activating NK receptor; killer cell lectin-like receptor subfamily C, member 3; Killer cell lectin like receptor C3

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