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Magic™ Membrane Protein Human MARCHF4 (Membrane associated ring-CH-type finger 4) Full Length (CAT#: MPC4118K) Made to Order

This product is a made-to-order Human MARCHF4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MARCHF4
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 2
  • Sequence
  • MLMPLCGLLWWWWCCCSGWYCYGLCAPAPQMLRHQGLLKCRCRMLFNDLK
    VFLLRRPPQAPLPMHGDPQPPGLAANNTLPALGAGGWAGWRGPREVVGRE
    PPPVPPPPPLPPSSVEDDWGGPATEPPASLLSSASSDDFCKEKTEDRYSL
    GSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISER
    GCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQVAAAILGSLFLIA
    SISWLIWSTFSPSARWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYR
    IFKRWQAVNQQWKVLNYDKTKDLEDQKAGGRTNPRTSSSTQANIPSSEEE
    TAGTPAPEQGPAQAAGHPSGPLSHHHCAYTILHILSHLRPHEQRSPPGSS
    RELVMRVTTV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • MARCHF4
  • Full Name
  • Membrane associated ring-CH-type finger 4
  • Introduction
  • MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment.
  • Alternative Names
  • MARCHF4; MARCH4; RNF174; MARCH-IV; E3 ubiquitin-protein ligase MARCHF4; RING finger protein 174; RING-type E3 ubiquitin transferase MARCH4; RING-type E3 ubiquitin transferase MARCHF4; membrane associated ring finger 4; membrane-associated RING finger protein 4; membrane-associated RING-CH protein IV; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; Membrane associated ring-CH-type finger 4

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