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Magic™ Membrane Protein Human NTSR2 (Neurotensin receptor 2) Full Length (CAT#: MPC0312K) Made to Order

This product is a 45.3 kDa Human NTSR2 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • NTSR2
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 45.3 kDa
  • TMD
  • 7
  • Sequence
  • METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGN
    ALSAHVVLKARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYP
    WVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPR
    RTRWLVALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTVLVSR
    TALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSST
    PSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLR
    AIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVS
    SAVTPLLYNAVSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTAS
    GFGDPPETRT

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • NTSR2
  • Full Name
  • Neurotensin receptor 2
  • Introduction
  • The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
  • Alternative Names
  • NTR2; neurotensin receptor type 2; NT-R-2; levocabastine-sensitive neurotensin receptor; neurotensin receptor, type 2; NTSR2; Neurotensin receptor 2

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