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Magic™ Membrane Protein Human PIGN (Phosphatidylinositol glycan anchor biosynthesis class N) Full Length (CAT#: MPC4501K) Made to Order

This product is a made-to-order Human PIGN membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PIGN
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 15
  • Sequence
  • MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFV
    ADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVA
    LIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS
    GDHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKIN
    EEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYG
    NDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQ
    FDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLN
    NTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFN
    ILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIG
    FVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLL
    IQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLA
    FTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSL
    LLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEEL
    LVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVVPL
    LSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQET
    LQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFG
    TGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQ
    LTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMS
    MTIFLVFLNGLAQLLTTKKLRLCGKPKSHFM

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • PIGN
  • Full Name
  • Phosphatidylinositol glycan anchor biosynthesis class N
  • Introduction
  • This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported.
  • Alternative Names
  • PIGN; MCD4; MDC4; MCAHS; PIG-N; MCAHS1; GPI ethanolamine phosphate transferase 1; MCD4 homolog; phosphatidylinositol-glycan biosynthesis class N protein; Phosphatidylinositol glycan anchor biosynthesis class N

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