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Magic™ Membrane Protein Human PTPRU (Protein tyrosine phosphatase receptor type U) Full Length (CAT#: MPC1895K) Made to Order

This product is a 162.4 kDa Human PTPRU membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTPRU
  • Protein Length
  • Full length
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 162.4 kDa
  • TMD
  • 1
  • Sequence
  • MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQ
    WEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCV
    QFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAV
    STFWPNEYQVLFEALISPDRRGYMGLDDILLLSYPCAKAPHFSRLGDVEV
    NAGQNASFQCMAAGRAAEAERFLLQRQSGALVPAAGVRHISHRRFLATFP
    LAAVSRAEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPIAPPQLLRAGPT
    YLIIQLNTNSIIGDGPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPD
    TEYEISVLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKGLAFAEIQARQL
    TLQWEPLGYNVTRCHTYTVSLCYHYTLGSSHNQTIRECVKTEQGVSRYTI
    KNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLE
    DMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNET
    YHVFSNLHPGTTYLFSVRARTGKGFGQAALTEITTNISAPSFDYADMPSP
    LGESENTITVLLRPAQGRGAPISVYQVIVEEERARRLRREPGGQDCFPVP
    LTFEAALARGLVHYFGAELAASSLPEAMPFTVGDNQTYRGFWNPPLEPRK
    AYLIYFQAASHLKGETRLNCIRIARKAACKESKRPLEVSQRSEEMGLILG
    ICAGGLAVLILLLGAIIVIIRKGRDHYAYSYYPKPVNMTKATVNYRQEKT
    HMMSAVDRSFTDQSTLQEDERLGLSFMDTHGYSTRGDQRSGGVTEASSLL
    GGSPRRPCGRKGSPYHTGQLHPAVRVADLLQHINQMKTAEGYGFKQEYES
    FFEGWDATKKKDKVKGSRQEPMPAYDRHRVKLHPMLGDPNADYINANYID
    GYHRSNHFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCSR
    YWPEDSDTYGDIKIMLVKTETLAEYVVRTFALERRGYSARHEVRQFHFTA
    WPEHGVPYHATGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLDV
    MLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACLCGET
    TIPVSEFKATYKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVEECSIALL
    PRNRDKNRSMDVLPPDRCLPFLISTDGDSNNYINAALTDSYTRSAAFIVT
    LHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQY
    GLMEVEFMSGTADEDLVARVFRVQNISRLQEGHLLVRHFQFLRWSAYRDT
    PDSKKAFLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGTFCACATVLEMI
    RCHNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLEGLESR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • PTPRU
  • Full Name
  • Protein tyrosine phosphatase receptor type U
  • Introduction
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.
  • Alternative Names
  • PTPRU; FMI; PTP; PCP-2; PTP-J; PTPRO; PTPU2; PTP-PI; PTP-RO; PTPPSI; hPTP-J; R-PTP-U; R-PTP-PSI; receptor-type tyrosine-protein phosphatase U; PTP pi; Receptor protein tyrosine phosphatase hPTP-J; pancreatic carcinoma phosphatase 2; pi R-PTP-Psi; protein-tyrosine phosphatase J; protein-tyrosine phosphatase pi; protein-tyrosine phosphatase receptor omicron; receptor-type protein-tyrosine phosphatase psi; Protein tyrosine phosphatase receptor type U

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