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Magic™ Membrane Protein Human RNF19A (Ring finger protein 19A, RBR E3 ubiquitin protein ligase) Full Length (CAT#: MPC4708K) Made to Order

Datasheet
This product is a made-to-order Human RNF19A membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RNF19A
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 2
  • Sequence
  • MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASS
    VSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSE
    MCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTC
    HHRSCVDCLRQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEK
    YEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTCGREGCGTEF
    CYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
    CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFW
    GKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHN
    RYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVV
    PISLCRSGGCGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHN
    PSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMALAGASITGSL
    SGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
    LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSS
    SGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQ
    QSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDY
    HTRFATVNILPEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHG
    NNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • RNF19A
  • Full Name
  • Ring finger protein 19A, RBR E3 ubiquitin protein ligase
  • Introduction
  • This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • RNF19A; RNF19; E3 ubiquitin-protein ligase RNF19A; double ring-finger protein; protein p38 interacting with transcription factor Sp1; ring finger protein 19A, E3 ubiquitin protein ligase; ring-IBR-ring domain containing protein Dorfin; Ring finger protein 19A, RBR E3 ubiquitin protein ligase

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