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Magic™ Membrane Protein Human SACM1L (SAC1 like phosphatidylinositide phosphatase) Full Length (CAT#: MPC2657K) Made to Order

Datasheet
This product is a made-to-order Human SACM1L membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SACM1L
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 2
  • Sequence
  • MATAAYEQLKLHITPEKFYVEACDDGADDVLTIDRVSTEVTLAVKKDVPP
    SAVTRPIFGILGTIHLVAGNYLIVITKKIKVGEFFSHVVWKATDFDVLSY
    KKTMLHLTDIQLQDNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTS
    PEFQEMSLLERADQRFVWNGHLLRELSAQPEVHRFALPVLHGFITMHSCS
    INGKYFDWILISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYNGSK
    ASFVQTRGSIPVFWSQRPNLKYKPLPQISKVANHMDGFQRHFDSQVIIYG
    KQVIINLINQKGSEKPLEQTFATMVSSLGSGMMRYIAFDFHKECKNMRWD
    RLSILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQ
    SLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYA
    GTGALKTDFTRTGKRTHLGLIMDGWNSMIRYYKNNFSDGFRQDSIDLFLG
    NYSVDELESHSPLSVPRDWKFLALPIIMVVAFSMCIICLLMAGDTWTETL
    AYVLFWGVASIGTFFIILYNGKDFVDAPRLVQKEKID

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SACM1L
  • Full Name
  • SAC1 like phosphatidylinositide phosphatase
  • Introduction
  • This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other studies suggest that this gene is also involved in the organization of golgi membranes and mitotic spindles. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame, downstream translation termination codon via a stop codon readthrough mechanism.
  • Alternative Names
  • SACM1L; SAC1; phosphatidylinositol-3-phosphatase SAC1; SAC1 suppressor of actin mutations 1 like; phosphatidylinositide phosphatase SAC1; phosphatidylinositol-4-phosphate phosphatase; suppressor of actin 1; suppressor of actin mutations 1-like protein; SAC1 like phosphatidylinositide phosphatase

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