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Magic™ Membrane Protein Human SCN10A (Sodium voltage-gated channel alpha subunit 10) Full Length (CAT#: MPC0697K) Made to Order

This product is a 220.6 kDa Human SCN10A membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SCN10A
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 220.6 kDa
  • TMD
  • 24
  • Sequence
  • MEFPIGSLETNNFRRFTPESLVEIEKQIAAKQGTKKAREKHREQKDQEEK
    PRPQLDLKACNQLPKFYGELPAELIGEPLEDLDPFYSTHRTFMVLNKGRT
    ISRFSATRALWLFSPFNLIRRTAIKVSVHSWFSLFITVTILVNCVCMTRT
    DLPEKIEYVFTVIYTFEALIKILARGFCLNEFTYLRDPWNWLDFSVITLA
    YVGTAIDLRGISGLRTFRVLRALKTVSVIPGLKVIVGALIHSVKKLADVT
    ILTIFCLSVFALVGLQLFKGNLKNKCVKNDMAVNETTNYSSHRKPDIYIN
    KRGTSDPLLCGNGSDSGHCPDGYICLKTSDNPDFNYTSFDSFAWAFLSLF
    RLMTQDSWERLYQQTLRTSGKIYMIFFVLVIFLGSFYLVNLILAVVTMAY
    EEQNQATTDEIEAKEKKFQEALEMLRKEQEVLAALGIDTTSLHSHNGSPL
    TSKNASERRHRIKPRVSEGSTEDNKSPRSDPYNQRRMSFLGLASGKRRAS
    HGSVFHFRSPGRDISLPEGVTDDGVFPGDHESHRGSLLLGGGAGQQGPLP
    RSPLPQPSNPDSRHGEDEHQPPPTSELAPGAVDVSAFDAGQKKTFLSAEY
    LDEPFRAQRAMSVVSIITSVLEELEESEQKCPPCLTSLSQKYLIWDCCPM
    WVKLKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIG
    NIVFTIFFTAEMVFKIIAFDPYYYFQKKWNIFDCIIVTVSLLELGVAKKG
    SLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTIILAIIVFV
    FALVGKQLLGENYRNNRKNISAPHEDWPRWHMHDFFHSFLIVFRILCGEW
    IENMWACMEVGQKSICLILFLTVMVLGNLVVLNLFIALLLNSFSADNLTA
    PEDDGEVNNLQVALARIQVFGHRTKQALCSFFSRSCPFPQPKAEPELVVK
    LPLSSSKAENHIAANTARGSSGGLQAPRGPRDEHSDFIANPTVWVSVPIA
    EGESDLDDLEDDGGEDAQSFQQEVIPKGQQEQLQQVERCGDHLTPRSPGT
    GTSSEDLAPSLGETWKDESVPQVPAEGVDDTSSSEGSTVDCLDPEEILRK
    IPELADDLEEPDDCFTEGCIRHCPCCKLDTTKSPWDVGWQVRKTCYRIVE
    HSWFESFIIFMILLSSGSLAFEDYYLDQKPTVKALLEYTDRVFTFIFVFE
    MLLKWVAYGFKKYFTNAWCWLDFLIVNISLISLTAKILEYSEVAPIKALR
    TLRALRPLRALSRFEGMRVVVDALVGAIPSIMNVLLVCLIFWLIFSIMGV
    NLFAGKFWRCINYTDGEFSLVPLSIVNNKSDCKIQNSTGSFFWVNVKVNF
    DNVAMGYLALLQVATFKGWMDIMYAAVDSREVNMQPKWEDNVYMYLYFVI
    FIIFGGFFTLNLFVGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLG
    SKKPQKPIPRPLNKFQGFVFDIVTRQAFDITIMVLICLNMITMMVETDDQ
    SEEKTKILGKINQFFVAVFTGECVMKMFALRQYYFTNGWNVFDFIVVVLS
    IASLIFSAILKSLQSYFSPTLFRVIRLARIGRILRLIRAAKGIRTLLFAL
    MMSLPALFNIGLLLFLVMFIYSIFGMSSFPHVRWEAGIDDMFNFQTFANS
    MLCLFQITTSAGWDGLLSPILNTGPPYCDPNLPNSNGTRGDCGSPAVGII
    FFTTYIIISFLIMVNMYIAVILENFNVATEESTEPLSEDDFDMFYETWEK
    FDPEATQFITFSALSDFADTLSGPLRIPKPNRNILIQMDLPLVPGDKIHC
    LDILFAFTKNVLGESGELDSLKANMEEKFMATNLSKSSYEPIATTLRWKQ
    EDISATVIQKAYRSYVLHRSMALSNTPCVPRAEEEAASLPDEGFVAFTAN
    ENCVLPDKSETASATSFPPSYESVTRGLSDRVNMRTSSSIQNEDEATSME
    LIAPGP

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SCN10A
  • Full Name
  • Sodium voltage-gated channel alpha subunit 10
  • Introduction
  • The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • PN3; SNS; FEPS2; Nav1.8; sodium channel protein type 10 subunit alpha; peripheral nerve sodium channel 3; sodium channel protein type X subunit alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.8; SCN10A; Sodium voltage-gated channel alpha subunit 10

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