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Magic™ Membrane Protein Human SLC26A5 (Solute carrier family 26 member 5) Full Length (CAT#: MPC0793K) Made to Order

Datasheet
This product is a 81.2 kDa Human SLC26A5 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC26A5
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 81.2 kDa
  • TMD
  • 12
  • Sequence
  • MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAF
    TCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLA
    FAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVR
    LVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGF
    VAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAV
    LQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMG
    TGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVG
    FSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRS
    LVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKG
    MFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVI
    YRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSD
    LYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVD
    GEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVN
    FIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWE
    LLFHSIHDAVLGSQLREALAEQEASAPPSQEDLEPNATPATPEA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC26A5
  • Full Name
  • Solute carrier family 26 member 5
  • Introduction
  • This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • PRES; DFNB61; prestin; prestin (motor protein); solute carrier family 26 (anion exchanger), member 5; SLC26A5; Solute carrier family 26 member 5

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