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Magic™ Membrane Protein Human SLC39A14 (Solute carrier family 39 member 14) Full Length (CAT#: MPC0854K) Made to Order

Datasheet
This product is a 54.2 kDa Human SLC39A14 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC39A14
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 54.2 kDa
  • TMD
  • 6
  • Sequence
  • MKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHR
    YGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTA
    HNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSA
    VEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYS
    NALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNE
    HHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM
    VDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFI
    DGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALF
    FNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPEMNE
    VCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQIG

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC39A14
  • Full Name
  • Solute carrier family 39 member 14
  • Introduction
  • This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia.
  • Alternative Names
  • HCIN; NET34; ZIP14; cig19; HMNDYT2; LZT-Hs4; metal cation symporter ZIP14; LIV-1 subfamily of ZIP zinc transporter 4; Zinc transporter ZIP14; Zrt-, Irt-like protein 14; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; zrt- and Irt-like protein 14; SLC39A14; Solute carrier family 39 member 14

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