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Magic™ Membrane Protein Human SLC6A5 (Solute carrier family 6 member 5) Full Length (CAT#: MPC0896K) Made to Order

This product is a 87.4 kDa Human SLC6A5 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC6A5
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • Molecular Weight
  • 87.4 kDa
  • TMD
  • 12
  • Sequence
  • MDCSAPKEMNKLPANSPEAAAAQGHPDGPCAPRTSPEQELPAAAAPPPPR
    VPRSASTGAQTFQSADARACEAERPGVGSCKLSSPRAQAASAALRDLREA
    QGAQASPPPGSSGPGNALHCKIPFLRGPEGDANVSVGKGTLERNNTPVVG
    WVNMSQSTVVLATDGITSVLPGSVATVATQEDEQGDENKARGNWSSKLDF
    ILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVS
    LGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFA
    SFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTA
    YPNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCL
    FLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGI
    WYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYR
    DTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVY
    PEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRT
    HKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELV
    GISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQW
    EPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKL
    VCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • SLC6A5
  • Full Name
  • Solute carrier family 6 member 5
  • Introduction
  • This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • NET1; GLYT2; HKPX3; GLYT-2; sodium- and chloride-dependent glycine transporter 2; solute carrier family 6 (neurotransmitter transporter, glycine), member 5; SLC6A5; Solute carrier family 6 member 5

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