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Magic™ Membrane Protein Human SPINT2 (Serine peptidase inhibitor, Kunitz type 2) Full Length (CAT#: MPC2451K) Made to Order

This product is a made-to-order Human SPINT2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SPINT2
  • Protein Length
  • Full length
  • Protein Class
  • Protease inhibitor
  • TMD
  • 1
  • Sequence
  • MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRAS
    MPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLA
    TSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY
    FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVV
    LAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTY
    VL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SPINT2
  • Full Name
  • Serine peptidase inhibitor, Kunitz type 2
  • Introduction
  • This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • SPINT2; PB; Kop; HAI2; DIAR3; HAI-2; kunitz-type protease inhibitor 2; hepatocyte growth factor activator inhibitor type 2; serine protease inhibitor, Kunitz type, 2; testicular tissue protein Li 183; Serine peptidase inhibitor, Kunitz type 2

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