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Magic™ Membrane Protein Human TNFRSF18 (TNF receptor superfamily member 18) Full Length (CAT#: MPC1988K) Made to Order

Datasheet
This product is a 26 kDa Human TNFRSF18 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TNFRSF18
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • Molecular Weight
  • 26 kDa
  • TMD
  • 1
  • Sequence
  • MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCC
    RVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGV
    QSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHN
    AVCVPGSPPAEPLGWLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPR
    ETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TNFRSF18
  • Full Name
  • TNF receptor superfamily member 18
  • Introduction
  • This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
  • Alternative Names
  • TNFRSF18; AITR; GITR; CD357; GITR-D; ENERGEN; tumor necrosis factor receptor superfamily member 18; TNF receptor superfamily activation-inducible protein; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily member 18

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