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Magic™ Membrane Protein Human TRPC4 (Transient receptor potential cation channel subfamily C member 4) Full Length (CAT#: MPC0957K) Made to Order

This product is a 112.1 kDa Human TRPC4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPC4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 112.1 kDa
  • TMD
  • 6
  • Sequence
  • MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKK
    SLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDAL
    LHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAA
    HTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIY
    KALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQ
    FAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF
    VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIA
    PKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPT
    IVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATIS
    LKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANS
    HLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCK
    GIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM
    FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEG
    GTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNL
    RRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEV
    LGLLRGSKLSTIQSANASKESSNSADSDEKSDSEGNSKDKKKNFSLFDLT
    TLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVTDIKNFGLFHR
    RSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP
    GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHA
    KEEDSSIDYDLNLPDTVTHEDYVTTRL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TRPC4
  • Full Name
  • Transient receptor potential cation channel subfamily C member 4
  • Introduction
  • This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Alternative Names
  • TRP4; HTRP4; HTRP-4; short transient receptor potential channel 4; trp-related protein 4; TRPC4; Transient receptor potential cation channel subfamily C member 4

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