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Magic™ Membrane Protein Human TRPM1 (Transient receptor potential cation channel subfamily M member 1) Full Length (CAT#: MPC0962K) Made to Order

This product is a 182.1 kDa Human TRPM1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPM1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 182.1 kDa
  • TMD
  • 6
  • Sequence
  • MKDSNRCCCGQFTNQHIPPLPSATPSKNEEESKQVETQPEKWSVAKHTQS
    YPTDSYGVLEFQGGGYSNKAMYIRVSYDTKPDSLLHLMVKDWQLELPKLL
    ISVHGGLQNFEMQPKLKQVFGKGLIKAAMTTGAWIFTGGVSTGVISHVGD
    ALKDHSSKSRGRVCAIGIAPWGIVENKEDLVGKDVTRVYQTMSNPLSKLS
    VLNNSHTHFILADNGTLGKYGAEVKLRRLLEKHISLQKINTRLGQGVPLV
    GLVVEGGPNVVSIVLEYLQEEPPIPVVICDGSGRASDILSFAHKYCEEGG
    IINESLREQLLVTIQKTFNYNKAQSHQLFAIIMECMKKKELVTVFRMGSE
    GQQDIEMAILTALLKGTNVSAPDQLSLALAWNRVDIARSQIFVFGPHWPP
    LGSLAPPTDSKATEKEKKPPMATTKGGRGKGKGKKKGKVKEEVEEETDPR
    KIELLNWVNALEQAMLDALVLDRVDFVKLLIENGVNMQHFLTIPRLEELY
    NTRLGPPNTLHLLVRDVKKSNLPPDYHISLIDIGLVLEYLMGGAYRCNYT
    RKNFRTLYNNLFGPKRPKALKLLGMEDDEPPAKGKKKKKKKKEEEIDIDV
    DDPAVSRFQYPFHELMVWAVLMKRQKMAVFLWQRGEESMAKALVACKLYK
    AMAHESSESDLVDDISQDLDNNSKDFGQLALELLDQSYKHDEQIAMKLLT
    YELKNWSNSTCLKLAVAAKHRDFIAHTCSQMLLTDMWMGRLRMRKNPGLK
    VIMGILLPPTILFLEFRTYDDFSYQTSKENEDGKEKEEENTDANADAGSR
    KGDEENEHKKQRSIPIGTKICEFYNAPIVKFWFYTISYLGYLLLFNYVIL
    VRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWN
    ITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIFWYIRVLDIFGVNK
    YLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLAR
    NIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPCIPGAW
    LTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMT
    FHDRPVLPPPMIILSHIYIIIMRLSGRCRKKREGDQEERDRGLKLFLSDE
    ELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEIN
    ERETFMKTSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRAS
    SECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGVRKK
    TCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAE
    ESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVIHGQDKSDVQNTQL
    TVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVG
    GVNQDVEYSSITDQQLTTEWQCQVQKITRSHSTDIPYIVSEAAVQAEHKE
    QFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRS
    KSLHGHPRNVKSIQGKLDRSGHASSVSSLVIVSGMTAEEKKVKKEKASTE
    TEC

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TRPM1
  • Full Name
  • Transient receptor potential cation channel subfamily M member 1
  • Introduction
  • This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • MLSN1; CSNB1C; LTRPC1; transient receptor potential cation channel subfamily M member 1; long transient receptor potential channel 1; melastatin-1; transient receptor potential melastatin family; TRPM1; Transient receptor potential cation channel subfamily M member 1

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