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Magic™ Membrane Protein Human TRPM2 (Transient receptor potential cation channel subfamily M member 2) Full Length (CAT#: MPC0963K) Made to Order

This product is a 171.1 kDa Human TRPM2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TRPM2
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 171.1 kDa
  • TMD
  • 6
  • Sequence
  • MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSWRLQCPF
    GNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLE
    EATKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTP
    SSVIYHLMTQHWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQT
    TGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIGVATWGTVHRR
    EGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP
    LRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPC
    VVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFETFTESRIV
    EWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHE
    NWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFV
    KLFLENGVQLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACA
    PAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQ
    GVSLRSLYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIA
    AALACSKILKELSKEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEER
    AQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVD
    NGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFH
    LNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYD
    PDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILS
    LDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGV
    AKQAILIHNERRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNG
    TDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTNILLLNLLIAMFNY
    TFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLSHLQLFIKRVVLK
    TPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQKIED
    ISNKVDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTAQALHWIVRTLRA
    SGFSSEADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNC
    PVTRFPVPNEKVPWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQ
    YNVVDGLRDRRSFHGPYTVQAGLPLNPMGRTGLRGRGSLSCFGPNHTLYP
    MVTRWRRNEDGAICRKSIKKMLEVLVVKLPLSEHWALPGGSREPGEMLPR
    KLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWIETVAVSVHFQ
    DQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAEFG
    AHY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • MBP tag at the N-terminus
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TRPM2
  • Full Name
  • Transient receptor potential cation channel subfamily M member 2
  • Introduction
  • The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known.
  • Alternative Names
  • KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; LTrpC-2; NUDT9L1; transient receptor potential cation channel subfamily M member 2; estrogen-responsive element-associated gene 1 protein; long transient receptor potential channel 2; transient receptor potential channel 7; transient receptor potential melastatin 2; TRPM2; Transient receptor potential cation channel subfamily M member 2

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