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Magic™ Recombinant Human SLC7A11 & SLC3A2 Membrane Protein in Virus-Like Particles (MP-VLPs) (CAT#: S01YF-0723-KX162)

Datasheet
This product is recombinant Human SLC7A11 & SLC3A2 in VLPs form.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC7A11 & SLC3A2
  • Protein Length
  • Full Length Heterodimer
  • Protein Class
  • Transporter
  • TMD
  • 12
  • Sequence
  • AA 2-501 (SLC7A11) & 2-630 (SLC3A2) (Accession # Q9UPY5 (SLC7A11) & P08195 (SLC3A2))

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; Antibody Production; Antibody Discovery; Antibody Characterization; Binding Assays; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Tag-free
  • Protein Format
  • Membrane Protein-Virus Like Particles (MP-VLPs)
  • Endotoxin
  • <1.0 EU per μg by the LAL method.
  • Buffer
  • PBS, Arginine, pH7.4

Target

  • Target Protein
  • SLC7A11 & SLC3A2
  • Full Name
  • Solute carrier family 7 member 11
  • Introduction
  • This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
  • Alternative Names
  • xCT; CCBR1; cystine/glutamate transporter; amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; SLC7A11; Solute carrier family 7 member 11

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