Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
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HighlightsGuinea pig is a commonly used laboratory animal. Biological experiments using guinea pigs have been recorded since the 17th century. In the 19th and 20th centuries, guinea pigs were used as model organisms. The guinea pig has made significant contributions in conducting discovery and research on diseases such as bone marrow injury, juvenile diabetes, and tuberculosis. With the unique advantages of the guinea pig, monoclonal guinea pig antibodies play an indispensable role in biochemical and pharmaceutical research. Based on our rich field experience and advanced antibody preparation platform, Creative Biolabs provides comprehensive antibody discovery services to support monoclonal guinea pig antibody production.
Guinea pigs share many physiological similarities with humans. They are ideal animals for immunological research experiments. Like humans, guinea pigs are unable to synthesize vitamin C in their bodies and rely on food intake, making them susceptible to scurvy. Therefore, guinea pigs are also ideal animal models for studying scurvy and the physiological function of vitamin C. They are also the standard animals for the biological assay of vitamin C.
Guinea pigs are very sensitive to a variety of pathogens and antibiotic drugs, so they are commonly used for pathogen isolation, diagnosis, and efficacy studies. For example, guinea pigs are highly sensitive to Mycobacterium tuberculosis, with a delayed-type hypersensitivity reaction similar to that of humans, and are therefore also commonly used in the isolation of Mycobacterium tuberculosis for differential diagnosis, screening of anti-tuberculosis drugs, and pathologic studies. They are also used exclusively to study the efficacy of antibiotics such as penicillin, erythromycin, and aureomycin, as well as anesthetic and asthma medications. Among the commonly used laboratory animals, guinea pigs are the most sensitive to allergenic substances. Re-exposure of guinea pigs that have already induced an allergic reaction to an antigen causes an acute reaction of bronchial smooth muscle contraction or even death, making them suitable for the study of allergic respiratory diseases. An animal model of anaphylaxis can be easily replicated by injecting guinea pigs with horse serum. They are sensitive to stimulation by toxic substances, approximating humans. Moreover, guinea pigs are in heat throughout the year, have a long gestation period, and have large fetuses, making them suitable for tests on the effects of drugs or toxic substances on fetal development as well as for studies on pregnancy complications.
As guinea pigs have so many advantages as laboratory animals, it is natural that monoclonal guinea pig antibodies can play an important role in the diagnosis and treatment of many related diseases, such as spinal cord injury, juvenile diabetes, tuberculosis, scurvy, pregnancy complications, and other common human diseases. Differences in genotype allow guinea pigs to produce stronger antibody responses to several antigens that are highly homologous to humans, mice, and rats. In this way, the production of monoclonal guinea pig antibodies may provide new solutions for some specific targets. In this way, phage display-based technology can significantly shorten the cycle of monoclonal antibody development. After the phage display library construction, the target antibody can be screened according to the needs of the experiment. Immune antibody library is also an important way to prepare monoclonal guinea pig antibodies. The higher rate of antibody libraries encoding functional antibodies capable of recognizing specific immunogens means that functional antibodies and their genes against immunogens can be screened from libraries with smaller library capacities. As a result, the abundance of immunizing antibody libraries specific to the corresponding immunogen is much higher than that of other non-specific antibodies compared to natural antibody libraries.
Creative Biolabs has a wealth of knowledge and experience in monoclonal antibody discovery. We would be happy to share with you our knowledge and experience related to monoclonal guinea pig antibody discovery.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
