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NativeExtract™ Human CNR2 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX466)

Datasheet
This product is recombinant Human CNR2 protein in native nanodisc form. The synthetic compound we developed can solubilize the CNR2 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CNR2
  • Protein Length
  • Full length
  • Molecular Weight
  • 39.7 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CNR2
  • Full Name
  • Cannabinoid receptor 2
  • Introduction
  • The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
  • Alternative Names
  • CB2; CX5; CB-2; cannabinoid receptor 2 (macrophage); CNR2; Cannabinoid receptor 2

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