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NativeExtract™ Human FZD10 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX446)

Datasheet
This product is recombinant Human FZD10 protein in native nanodisc form. The synthetic compound we developed can solubilize the FZD10 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FZD10
  • Protein Length
  • Full length
  • Molecular Weight
  • 65.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • FZD10
  • Full Name
  • Frizzled class receptor 10
  • Introduction
  • This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
  • Alternative Names
  • Fz10; FzE7; CD350; FZ-10; hFz10; frizzled-10; frizzled 10, seven transmembrane spanning receptor; frizzled family receptor 10; frizzled homolog 10; FZD10; Frizzled class receptor 10

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