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NativeExtract™ Human GPR143 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX247)

Datasheet
This product is recombinant Human GPR143 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR143 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR143
  • Protein Length
  • Full length
  • Molecular Weight
  • 43.9kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR143
  • Full Name
  • G protein-coupled receptor 143
  • Introduction
  • This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.
  • Alternative Names
  • OA1; NYS6; G-protein coupled receptor 143; ocular albinism 1; ocular albinism type 1 protein; GPR143; G protein-coupled receptor 143

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