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NativeExtract™ Human GPR50 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX155)

Datasheet
This product is recombinant Human GPR50 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR50 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR50
  • Protein Length
  • Full length
  • Molecular Weight
  • 67.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR50
  • Full Name
  • G protein-coupled receptor 50
  • Introduction
  • This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.
  • Alternative Names
  • H9; Mel1c; melatonin-related receptor; GPR50; G protein-coupled receptor 50

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