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NativeExtract™ Human HRH4 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX181)

Datasheet
This product is recombinant Human HRH4 protein in native nanodisc form. The synthetic compound we developed can solubilize the HRH4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • HRH4
  • Protein Length
  • Full length
  • Molecular Weight
  • 44.5kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • HRH4
  • Full Name
  • Histamine receptor H4
  • Introduction
  • Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105; histamine H4 receptor; G-protein coupled receptor 105; SP9144; pfi-013; HRH4; Histamine receptor H4

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