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NativeExtract™ Human LGR5 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX443)

Datasheet
This product is recombinant Human LGR5 protein in native nanodisc form. The synthetic compound we developed can solubilize the LGR5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LGR5
  • Protein Length
  • Full length
  • Molecular Weight
  • 100.0 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • LGR5
  • Full Name
  • Leucine rich repeat containing G protein-coupled receptor 5
  • Introduction
  • The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
  • Alternative Names
  • FEX; HG38; GPR49; GPR67; GRP49; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; orphan G protein-coupled receptor HG38; LGR5; Leucine rich repeat containing G protein-coupled receptor 5

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