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NativeExtract™ Human MCHR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX166)

Datasheet
This product is recombinant Human MCHR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the MCHR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MCHR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 46kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • MCHR1
  • Full Name
  • Melanin concentrating hormone receptor 1
  • Introduction
  • The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
  • Alternative Names
  • SLC1; GPR24; MCH1R; SLC-1; MCH-1R; G protein-coupled receptor 24; MCH receptor 1; somatostatin receptor-like protein; MCHR1; Melanin concentrating hormone receptor 1

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