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NativeExtract™ Human MLC1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX459)

Datasheet
This product is recombinant Human MLC1 protein in native nanodisc form. The synthetic compound we developed can solubilize the MLC1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MLC1
  • Protein Length
  • Full length
  • Molecular Weight
  • 41.2 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • MLC1
  • Full Name
  • Modulator of VRAC current 1
  • Introduction
  • The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • MLC1; VL; LVM; MLC; membrane protein MLC1; megalencephalic leukoencephalopathy with subcortical cysts 1; Modulator of VRAC current 1

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