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NativeExtract™ Human MTNR1B Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX156)

This product is recombinant Human MTNR1B protein in native nanodisc form. The synthetic compound we developed can solubilize the MTNR1B protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • MTNR1B
  • Protein Length
  • Full length
  • Molecular Weight
  • 40.2kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • MTNR1B
  • Full Name
  • Melatonin receptor 1B
  • Introduction
  • This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
  • Alternative Names
  • MT2; FGQTL2; MEL-1B-R; melatonin receptor type 1B; mel1b receptor; melatonin receptor 1B variant b; melatonin receptor MEL1B; MTNR1B; Melatonin receptor 1B

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