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NativeExtract™ Human SLC4A7 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX417)

Datasheet
This product is recombinant Human SLC4A7 protein in native nanodisc form. The synthetic compound we developed can solubilize the SLC4A7 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC4A7
  • Protein Length
  • Full length
  • Molecular Weight
  • 136.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • SLC4A7
  • Full Name
  • Solute carrier family 4 member 7
  • Introduction
  • This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.
  • Alternative Names
  • NBC2; NBC3; SBC2; NBCN1; SLC4A6; sodium bicarbonate cotransporter 3; bicarbonate transporter; electroneutral Na/HCO(3) cotransporter; sodium bicarbonate cotransporter 2; sodium bicarbonate cotransporter 2b; solute carrier family 4, sodium bicarbonate cotransporter, member 7; SLC4A7; Solute carrier family 4 member 7

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