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Precision Antibody Replication Services

Overview Workflow Service Features

After years of antibody development, Creative Biolabs has developed mouse and rat hybridoma technology, B-cell cloning strategies from rabbits, and even diverse species such as chicken and more. We will integrate antigen design, immunization, and screening tools to exploit these traits. We can select the best approach in partnership with you to deliver an antibody that not only binds but also works in the way you need it to.

Overview of Precision Antibody Replication

Antigens are molecules that trigger an immune response, containing antigenic determinants, or epitopes, recognized by antibodies. Antigenic determinants, or epitopes, are particular areas of antigens that engage with antibodies or T-cell receptors to elicit immunological responses. Epitopes can be linear (sequential amino acids) or conformational (folded protein regions). They are crucial for immune identification and response. Antibody paratopes can bind to the epitope of an antigen. Precise replication ensures the accurate reproduction of antibodies that specifically target epitopes, allowing for effective immune responses against pathogens. This process is crucial in vaccine development, diagnostics, and therapeutics, facilitating the creation of customized antibodies to combat particular diseases. By understanding antigenic determinants and epitopes, it is possible to design vaccines and treatments to elicit precise immune responses, enhancing their efficacy and minimizing adverse effects.

Fig.1 Antigen epitope recognition by antibodies paratopes. (Bukhari, et al., 2022)Fig.1 Antigen recognition by antibodies: interactions between epitopes and paratopes.1

Workflow of Precision Antibody Replication

Precision antibody replication involves the faithful reproduction of antibodies designed to identify and bind to accurate antigenic epitopes. Techniques such as X-ray crystallography and mutagenesis studies help determine these epitopes, facilitating targeted antibody development for precise immune targeting.

Fig.2 The process of precision antibody replication. (Creative Biolabs Original)Fig.2 Precision antibody replication service workflow.

Precision Antibody Replication Service

For commercial monoclonal antibodies or reported antibody candidates with epitope information, Creative Biolabs provides precise antibody replication services. Through our professional epitope determination technology and mature antibody production solutions, you can obtain satisfactory customized antibodies. Immunogen design service is one of our core technical services. We offer complementary protein expression or peptide design services to generate custom antibodies with better performance.

Features of Our Service


To solve the recurrence crisis of antibodies and improve the speed of antibody development, Creative Biolabs provides innovative precision antibody replication services for worldwide clients. If you are interested in learning more about our immunogen design services, please contact us directly. One of our experts will contact you shortly.

Reference
  1. Bukhari, Syed Nisar Hussain, et al. "Machine learning techniques for the prediction of B-cell and T-cell epitopes as potential vaccine targets with a specific focus on SARS-CoV-2 pathogen: A review." Pathogens 11.2 (2022): 146.
    Distributed under Open Access license CC BY 4.0, without modification.

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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