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P2RY12

This gene encodes a member of the G-protein coupled receptor family. There are multiple receptor subtypes in this family that have overlapping pharmacological selectivity for diverse adenosine and uridine nucleotides. The potential target of this receptor in the therapy of thromboembolisms and other clotting disorders is its role in platelet aggregation. This gene's mutations are linked to platelet type 8 bleeding disorders.

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