Human LRP6 Protein (Glu 631-Thr 1363) [Fc] (VAng-1902Lsx)
Human LRP6 protein, Mouse IgG2a Fc Tag, expressed in human 293 cells. (Uniprot ID: O75581-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
LRP6
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
LRP6 (LDL Receptor Related Protein 6) is a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types.
Alternative Names
LRP-6, LRP6
Related Product
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