Human RENIN Protein (Leu 24-Arg 406) [His] (VAng-2652Lsx)
Human RENIN protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH33474)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
REN (Renin) catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release, vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance.
Alternative Names
REN, FLJ10761, Renin, angiotensinogenase
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