Human RSPO1 Protein (Ser 21-Ala 146) [His] (VAng-2669Lsx)
Human RSPO1 protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAI1496)
Datasheet
Specifications
Source
HEK293 cells
Target
RSPO1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
RSPO1 (R-Spondin 1) is a a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
Alternative Names
RSPO1, CRISTIN3, FLJ40906, RP11-566C13.1, R-spondin-1
Related Product
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