Inactivated sIPV-1 Antigen (VAng-Lsx0440)
Salk Inactivated poliovirus type 1, inactivated native antigen.
Datasheet
Specifications
Target
Poliovirus
Type
Viral Antigens
Applications
ELISA, WB, SDS-PAGE, Immunogen, etc.
Purity
> 90 % pure by SDS-PAGE.
Storage
Store at 4 °C.
Antigen Information
Introduction
There are two types of Polio vaccines: one that use sinactivated poliovirus and is given by injection (IPV), and one that uses weakened poliovirus and is given by mouth (OPV). The Salk vaccine, or inactivated poliovirus vaccine (IPV), is based on three wild, virulent reference strains, Mahoney (type 1 poliovirus), MEF-1 (type 2 poliovirus), and Saukett (type 3 poliovirus), grown in a type of monkey kidney tissue culture (Vero cell line), which are then inactivated with formalin. The injected Salk vaccine confers IgG-mediated immunity in the bloodstream, which prevents polio infection from progressing to viremia and protects the motor neurons, thus eliminating the risk of bulbar polio and post-polio syndrome.
Alternative Names
Salk Inactivated poliovirus; Salk poliovirus; Inactivated poliovirus
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
