nBu-PGA(50)[Prg(20)] (VCar-Ly275)
nBu-PGA(50)[Prg(20)], 7500 Da, n-Butyl-poly(L-glutamic acid gamma-propargyl amide) sodium salt, a poly-glutamic acid (PGA) derivative with the features of water-soluble, anionic and biodegradable.
Applications
A polymer that can be uesd as versatile biodegradable drug carrier polyglutamates.
Introduction
Polyglutamic acid (PGA) is a polymer of the amino acid glutamic acid (GA) which owns the special interest based on its biodegradability, non-dangerous and non-immunogenic properties. Therefore, PGA exhibited many therapeutic applications as anticancer agent, drug delivery, biological glues, biological control agent, and in tissue engineering.
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