Recombinant Chlorocebus aethiops Cathepsin L Protein (aa 114-333) [His] (VAng-4234Lsx)
Recombinant Chlorocebus aethiops Cathepsin L (CTSL1) protein, expressed in E. coli. (Uniprot ID: Q9GKL8)
Datasheet
Specifications
Source
E. coli
Target
Cathepsin L
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
20 mM Tris-HCl based buffer, pH 8.0.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CTSL (Cathepsin L) is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor.
Alternative Names
CTSL1, MEP, CATL, CTSL
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
