Recombinant HCV Core, NS3, NS4 and NS5 Protein [His] (VAng-Lsx0206)
Recombinant Hepatitis C virus Core antigen, contains the HCV core, NS3, NS4 and NS5 immunodominant regions and a 6-His fusion partner, was expressed in E. coli, and puried in vitro using proprietary chromatographic technique.
Applications
ELISA, WB, SDS-PAGE, Immunogen, etc.
Formulation
50mM Tris-HCl, pH 8.0 containing 8M Urea, 0.5mM EDTA and 0.15mM DTT.
Purity
> 95 % pure by 10 % SDS-PAGE.
Storage
Store at 2 °C to 8 °C short term, -20 °C long term.
Introduction
Hepatitis C virus (HCV) is a member of the Flaviviridae family, genus hepacivirus. HCV is a small (55-65 nm in size), enveloped, positive-sense single-stranded RNA virus. E1 and E2 are two type 1 transmembrane glycoproteins that are essential components of the envelope. They can assemble as non-covalent heterodimers and are necessary for viral entry and fusion. Hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans.
Alternative Names
Core protein p19; HCcAg; HCV core antigen; HCV core protein; Hepatitis C Virus core protein
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.