4-1BB
4-1BB is a member of the tumor necrosis factor (TNF) receptor family. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule. It can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, 4-1BB expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. The best characterized activity of 4-1BB is its costimulatory activity for activated T cells. Crosslinking of 4-1BB enhances T cell proliferation, IL-2 secretion, survival and cytolytic activity.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3827 | Recombinant 4-1BB Protein (Met1-Gln186) [His] | Mammalian cells | Recombinant 4-1BB Protein (Met1-Gln186) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 30 kDa. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens |  |
100 µg | Inquiry |
| VAng-0680Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Val 29-Ile 191) [His] | HEK293 Cells. | Rabbit 4-1BB Protein (Val 29-Ile 191) fused with a His tag at C-terminus was expressed in HEK 293 cells, with a molecular weight of 27-33 kDa. (Uniprot ID: G1SHD7) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-0681Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) | HEK293 Cells. | Human 4-1BB low endotoxin was expressed in HEK 293 cells, with a molecular weight of 28-35 kDa. (Uniprot ID: Q07011-1) | 4-1BB | Tumor Antigens | |
1 mg | Inquiry |
| VAng-0682Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [Fc] | HEK293 Cells. | Human 4-1BB low endotoxin with a Mouse IgG2a Fc Tag was expressed in HEK 293 cells, with a molecular weight of 55-66 kDa. (Uniprot ID: Q07011-1) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-0683Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [Avi] [His] | HEK293 Cells. | Biotinylated Human 4-1BB, Avi tag, His Tag, was expressed in HEK 293 cells, with a molecular weight of 28-35 kDa. (Uniprot ID: NP_001552.2) | 4-1BB | Tumor Antigens | |
25 µg | Inquiry |
| VAng-0684Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [Avi] [Fc] | HEK293 Cells. | Biotinylated Human 4-1BB, Avi tag, Fc Tag, was expressed in HEK 293 cells, with a molecular weight of 55-60 kDa. (Uniprot ID: NP_001552.2) | 4-1BB | Tumor Antigens | |
25 µg | Inquiry |
| VAng-0685Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Val 24-Leu 211) [Fc] | HEK293 Cells. | Mouse 4-1BB, Fc tag, was expressed in HEK 293 cells, with a molecular weight of 46.7 kDa. (Uniprot ID: NP_001070976) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-0686Lsx | Cynomolgus / Rhesus macaque 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [His] | HEK293 Cells. | Cynomolgus / Rhesus macaque 4-1BB, His tag, was expressed in HEK 293 cells, with a molecular weight of 19.2 kDa. (Uniprot ID: XP_005544945.1) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-0687Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Gln 25-Gln 186) [Fc] | HEK293 Cells. | Human 4-1BB, Fc Tag, was expressed in HEK 293 cells, with a molecular weight of 43.3 kDa. (Uniprot ID: NP_001552.2) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-0688Lsx | Human 4-1BB / TNFRSF9 Protein (Leu 24-Gln 186) [His] | HEK293 Cells. | Human 4-1BB, His Tag, was expressed in HEK 293 cells, with a molecular weight of 19.2 kDa. (Uniprot ID: Q07011-1) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-2776Lsx | Recombinant 4-1BB / TNFRSF9 Protein | E. coli | Recombinant 4-1BB / TNFRSF9 Protein was expressed in E. coli. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens | |
20 µg | Inquiry |
| VAng-2777Lsx | Recombinant 4-1BB / TNFRSF9 Protein (aa 1-185) [Fc] | E. coli | Recombinant 4-1BB / TNFRSF9 Protein was expressed in E. coli. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens | |
50 µg | Inquiry |
| VAng-2778Lsx | Recombinant Mouse 4-1BB / TNFRSF9 Protein (aa 24-256) | Cell Free Expression | Recombinant 4-1BB / TNFRSF9 Protein was expressed in cell free expression systems. (Uniprot ID: P20334) | 4-1BB | Tumor Antigens | |
50 µg | Inquiry |
| VAng-2779Lsx | Recombinant 4-1BB Protein (aa 1-186) [Fc] | HEK 293 Cells | Recombinant 4-1BB Protein, fused to the Fc portion of human IgG1, was expressed in HEK 293 cells. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens | |
50 µg | Inquiry |
| VAng-2780Lsx | Recombinant Human 4-1BB / TNFRSF9 Protein (aa 52-254) [His] | E. coli | Recombinant human 4-1BB / TNFRSF9 Protein, His tag, was expressed in E. coli. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-2781Lsx | Recombinant Mouse 4-1BB / TNFRSF9 Protein (aa 24-187) | E. coli | Recombinant mouse 4-1BB / TNFRSF9 Protein was expressed in E. coli. (Uniprot ID: P20334) | 4-1BB | Tumor Antigens | |
100 µg | Inquiry |
| VAng-2782Lsx | Recombinant 4-1BB / TNFRSF9 Protein (CHO cells) | CHO Cells | Recombinant 4-1BB / TNFRSF9 Protein was expressed in CHO cells. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens | |
200 µg | Inquiry |
| VAng-2783Lsx | Recombinant 4-1BB / TNFRSF9 Protein (aa 40-153) [His] | E. coli | Recombinant 4-1BB / TNFRSF9 Protein, His tag, was expressed in E. coli. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens | |
200 µg | Inquiry |
| VAng-2784Lsx | Recombinant Mouse 4-1BB / TNFRSF9 Protein (aa 24-187) [Fc] | HEK 293 Cells | Recombinant mouse 4-1BB / TNFRSF9 Protein was expressed in HEK 293 cells. (Uniprot ID: P20334) | 4-1BB | Tumor Antigens | |
50 µg | Inquiry |
| VAng-2785Lsx | Recombinant 4-1BB / TNFRSF9 Protein (Sf9 Baculovirus Cells) | Sf9 Insect Cells | Recombinant mouse 4-1BB / TNFRSF9 Protein was expressed in Sf9 Baculovirus Cells. (Uniprot ID: Q07011) | 4-1BB | Tumor Antigens | |
10 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
