LDLR

LDLR (Low Density Lipoprotein Receptor) are involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

CAT	Product Name	Source	Product Overview	Target	Type	Size	Price
VAng-1635Lsx	Biotinylated Human LDLR Protein (Ala 22-Arg 788) [His] [Avi]	HEK293 Cells.	Biotinylated Human LDLR protein, His tag and Avi tag, expressed in human 293 cells. (Uniprot ID: P01130-1)	LDLR	Tumor Antigens	25 µg	Inquiry
VAng-1661Lsx	Cynomolgus LDLR Protein (Ala 22-Gly 788) [His]	HEK293 Cells.	Cynomolgus LDLR protein, His tag, expressed in human 293 cells. (Uniprot ID: XP_005588053.1)	LDLR	Tumor Antigens	100 µg	Inquiry
VAng-1880Lsx	Human LDLR Protein (Ala 22-Arg 788) [Fc]	HEK293 Cells.	Human LDLR protein, Fc tag, expressed in human 293 cells. (Uniprot ID: NP_000518)	LDLR	Tumor Antigens	100 µg	Inquiry
VAng-1881Lsx	Human LDLR Protein (Ala 22-Arg 788) [His]	HEK293 Cells.	Human LDLR protein, His tag, expressed in human 293 cells. (Uniprot ID: NP_000518.1)	LDLR	Tumor Antigens	100 µg	Inquiry
VAng-1882Lsx	Human LDLR Protein (Ala 22-Arg 788) [Strep]	HEK293 Cells.	Human LDLR protein, Strep tag, expressed in human 293 cells. (Uniprot ID: NP_000518.1)	LDLR	Tumor Antigens	25 µg	Inquiry
VAng-1945Lsx	Mouse LDLR Protein (Ala 22-Arg 790) [His]	HEK293 Cells.	Mouse LDLR protein, His tag, expressed in human 293 cells. (Uniprot ID: NP_034830)	LDLR	Tumor Antigens	100 µg	Inquiry

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