Genetically-modified CIK Devlopment Services

The Urgency of CIK Improvement

Cytokine-induced killer (CIK) cells, a subset of effector natural killer T cells characterized by CD3⁺CD56⁺ markers, hold promise as a cancer immunotherapy. These cells exhibit potent, MHC-independent anti-tumor activity and can be easily expanded in vitro from peripheral blood mononuclear cells. However, their clinical efficacy is hindered by factors like the immunosuppressive tumor microenvironment, short cell persistence, and variable cytotoxicity. To maximize their therapeutic potential, ongoing research is dedicated to developing innovative strategies to address these limitations and broaden the application of CIK cell therapy.

Fig.1 CIK cells' capacity to identify cancer and combat it.¹

Our Genetically-modified CIK Development Services

Genetically modified CIK (GM-CIK) cells represent a promising approach in cancer immunotherapy. At Creative Biolabs, we offer comprehensive GM-CIK development services to advance your research and develop innovative therapies. Our services encompass multiple selective CIK genetic-engineering strategies, such as CAR-CIK cell engineering, cytokine-engineered CIK cells, CIK cells equipped with safety switches, and DC-CIK co-culture. By implementing specific genetic modifications, we are capable of enhancing CIK cells' anti-tumor activity, target specificity, and persistence. Our rigorous quality control system ensures the safety and efficacy of our GM-CIK products. Leveraging our advanced platform and experienced team, we are committed to delivering high-quality CIK products that meet your research needs.

Our Services Package

Why Choose Creative Biolabs

• Expertise: Our experienced scientists have a deep understanding of CIK cell biology and genetic engineering techniques.
• Advanced Technologies: We employ cutting-edge technology to assure the best quality and performance of our GM-CIK products.
• Regulatory Compliance: We adhere to strict regulatory guidelines and quality control standards to ensure the safety and efficacy of our products.
• Customized Solutions: We provide personalized solutions to match your unique research goals.

What Customer Say

Excellent

Da***l

Creative Biolabs has been an invaluable partner in our research on genetically modified CIK cells. Their team of experts provided comprehensive support throughout the entire process, from initial cell isolation and engineering to final cell expansion and characterization. The genetically modified CIK cells we received exhibited enhanced anti-tumor activity and prolonged persistence in preclinical models. The high quality of the cells, coupled with Creative Biolabs' efficient and reliable service, has significantly accelerated our research progress. We are optimistic about the potential of these advanced CIK cells to revolutionize cancer immunotherapy.

23/Apr/2024 5 Likes

Please don't hesitate to get in touch with us for more detailed information about our genetically-modified CIK development services.

Reference

1. Li, Celine Man Ying, et al. "Clinical application of cytokine-induced killer (CIK) cell therapy in colorectal cancer: Current strategies and future challenges." Cancer Treatment Reviews 122 (2024): 102665. Distributed under Open Access license CC BY 4.0, without modification.