EGFR

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane proteins are activated following binding with peptide growth factors of the EGF-family of proteins. Evidence suggests that the EGFR is involved in the pathogenesis and progression of different carcinoma types. The EGFR and EGF-like peptides are often over-expressed in human carcinomas. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including squamous-cell carcinoma of the lung (80% of cases), anal cancers, glioblastoma (50%) and epithelian tumors of the head and neck (80-100%).

EGFR Associated Disease
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP8476 A uniCAR [Anti-FITC CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8493 A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Cetuximab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
CAR-ZP8494 A uniCAR [Anti-CD16 CAR], with a mAb-based CAR Adaptor [Anti-EGFR (Panitumumab)], a Switchable CAR System Breast cancer Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9106 TS-Fluc Anti-Human EGFR scFv (XW-320) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-320 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9107 TS-Fluc Anti-Human EGFR scFv (XW-321) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-321 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9108 TS-Fluc Anti-Mouse EGFR scFv (XW-322) CD28-41BB-CD3ζ CAR, pCDCAR1 Mouse XW-322 Rabbit 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9109 TS-Fluc Anti-Mouse EGFR scFv (XW-323) CD28-41BB-CD3ζ CAR, pCDCAR1 Mouse XW-323 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9110 TS-Fluc Anti-Mouse EGFR scFv (XW-324) CD28-41BB-CD3ζ CAR, pCDCAR1 Mouse XW-324 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9111 TS-Fluc Anti-Mouse EGFR scFv (XW-325) CD28-41BB-CD3ζ CAR, pCDCAR1 Mouse XW-325 Rabbit 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9112 TS-Fluc Anti-Human EGFR scFv (XW-326) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-326 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9113 TS-Fluc Anti-Human EGFR scFv (XW-327) CD28-41BB-CD3ζ CAR, pCDCAR1 Human XW-327 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9516 TS-IL15 SA Anti-Human EGFR scFv (XW-321) CD28-CD3ζ CAR, pCDCAR1 Human XW-321 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9517 TS-IL15 SA Anti-Mouse EGFR scFv (XW-322) CD28-CD3ζ CAR, pCDCAR1 Mouse XW-322 Rabbit 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9518 TS-IL15 SA Anti-Mouse EGFR scFv (XW-323) CD28-CD3ζ CAR, pCDCAR1 Mouse XW-323 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9519 TS-IL15 SA Anti-Mouse EGFR scFv (XW-324) CD28-CD3ζ CAR, pCDCAR1 Mouse XW-324 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9520 TS-IL15 SA Anti-Mouse EGFR scFv (XW-325) CD28-CD3ζ CAR, pCDCAR1 Mouse XW-325 Rabbit 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9521 TS-IL15 SA Anti-Human EGFR scFv (XW-326) CD28-CD3ζ CAR, pCDCAR1 Human XW-326 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9522 TS-IL15 SA Anti-Human EGFR scFv (XW-327) CD28-CD3ζ CAR, pCDCAR1 Human XW-327 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9924 TS-IL15 SA Anti-Human EGFR scFv (XW-320) 41BB-CD3ζ CAR, pCDCAR1 Human XW-320 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9925 TS-IL15 SA Anti-Human EGFR scFv (XW-321) 41BB-CD3ζ CAR, pCDCAR1 Human XW-321 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9926 TS-IL15 SA Anti-Mouse EGFR scFv (XW-322) 41BB-CD3ζ CAR, pCDCAR1 Mouse XW-322 Rabbit 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9927 TS-IL15 SA Anti-Mouse EGFR scFv (XW-323) 41BB-CD3ζ CAR, pCDCAR1 Mouse XW-323 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
XS-0822-YF9928 TS-IL15 SA Anti-Mouse EGFR scFv (XW-324) 41BB-CD3ζ CAR, pCDCAR1 Mouse XW-324 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector   Add to Cart   Datasheet
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